{"id":206,"date":"2021-09-13T10:35:56","date_gmt":"2021-09-13T08:35:56","guid":{"rendered":"http:\/\/salinomycin.pl\/?page_id=206"},"modified":"2023-08-02T14:32:41","modified_gmt":"2023-08-02T12:32:41","slug":"cancer-steam-cell-csc","status":"publish","type":"page","link":"https:\/\/salinomycin.pl\/?page_id=206","title":{"rendered":"Cancer Steam Cell (CSC)"},"content":{"rendered":"

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Cancer Steam Cell (CSC)<\/h2>\n

Wsp\u00f3\u0142czesna onkologia pomimo wielu lat do\u015bwiadcze\u0144 w walce z rakiem ma jeszcze wiele problem\u00f3w do rozwi\u0105zania. Jednym z najwi\u0119kszych problem\u00f3w jest powr\u00f3t stanu chorobowego po zaprzestaniu przyjmowania lek\u00f3w. Za ten stan rzeczy odpowiedzialne s\u0105 macierzyste kom\u00f3rki nowotworowe (CSC), kt\u00f3re nie zostaj\u0105 zlikwidowane przez stosowane terapeutyki.<\/span><\/p>\n

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Salinomycyna mo\u017ce by\u0107 skutecznym lekiem w walce z macierzystymi kom\u00f3rkami nowotworowymi ze wzgl\u0119du na zdolno\u015b\u0107 przywracania parametr\u00f3w organizmu, kt\u00f3re zosta\u0142y zaburzone w procesie chorobowym do stanu sprzed choroby. Salinomycyna dzia\u0142a wielow\u0105tkowo. Ma zdolno\u015b\u0107 do obni\u017cania st\u0119\u017cenia enzym\u00f3w wyst\u0119puj\u0105cych w danych stanach chorobowych. Jest zdolna do indukowania apoptozy niepo\u017c\u0105danych kom\u00f3rek. Hamuje proliferacj\u0119, migracj\u0119, inwazyjno\u015b\u0107 i onkogenno\u015b\u0107 niekt\u00f3rych typ\u00f3w macierzystych kom\u00f3rek nowotworowych.<\/p>\n

Salinomycyna eliminuje macierzyste kom\u00f3rki nowotworowe 100 razy bardziej selektywnie ni\u017c lek przeciwnowotworowy paclitaxel (taksol).<\/p>\n

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\u0179r\u00f3d\u0142a :<\/strong><\/h2>\n

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Selectively Eradicate Cancer Stem Cells by a Small Molecule<\/strong>
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The inhibitory effect of salinomycin on the proliferation, migration and invasion…<\/strong>
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Semisynthesis of SY\u20111 for Investigation of Breast Cancer Stem Cell…<\/strong>
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Salinomycin as a Drug for Targeting Human Cancer Stem Cells<\/strong><\/h5>\n
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Metformin and salinomycin as the best combination for the…<\/strong>
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2017 EJMedChem Cancer<\/strong>
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Salinomycin as a Drug for Targeting Human Cancer Stem Cells<\/strong>
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HDAC inhibitors enhance the lethality of low dose salinomycin in parental and stem-like GBM cells<\/strong><\/h5>\n

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Cancer Steam Cell (CSC) Wsp\u00f3\u0142czesna onkologia pomimo wielu lat do\u015bwiadcze\u0144 w walce z rakiem ma jeszcze wiele problem\u00f3w do rozwi\u0105zania. Jednym z najwi\u0119kszych problem\u00f3w jest powr\u00f3t stanu chorobowego po zaprzestaniu przyjmowania lek\u00f3w. Za ten stan rzeczy odpowiedzialne s\u0105 macierzyste kom\u00f3rki nowotworowe (CSC), kt\u00f3re nie zostaj\u0105 zlikwidowane przez stosowane terapeutyki.    Salinomycyna mo\u017ce by\u0107 skutecznym lekiem […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-206","page","type-page","status-publish","hentry"],"yoast_head":"\nCancer Steam Cell (CSC) - Salinomycin<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/salinomycin.pl\/?page_id=206\" \/>\n<meta property=\"og:locale\" content=\"pl_PL\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cancer Steam Cell (CSC) - Salinomycin\" \/>\n<meta property=\"og:description\" content=\"Cancer Steam Cell (CSC) Wsp\u00f3\u0142czesna onkologia pomimo wielu lat do\u015bwiadcze\u0144 w walce z rakiem ma jeszcze wiele problem\u00f3w do rozwi\u0105zania. Jednym z najwi\u0119kszych problem\u00f3w jest powr\u00f3t stanu chorobowego po zaprzestaniu przyjmowania lek\u00f3w. Za ten stan rzeczy odpowiedzialne s\u0105 macierzyste kom\u00f3rki nowotworowe (CSC), kt\u00f3re nie zostaj\u0105 zlikwidowane przez stosowane terapeutyki.    Salinomycyna mo\u017ce by\u0107 skutecznym lekiem […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/salinomycin.pl\/?page_id=206\" \/>\n<meta property=\"og:site_name\" content=\"Salinomycin\" \/>\n<meta property=\"article:modified_time\" content=\"2023-08-02T12:32:41+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Szacowany czas czytania\" \/>\n\t<meta name=\"twitter:data1\" content=\"15 minut\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/salinomycin.pl\/?page_id=206\",\"url\":\"https:\/\/salinomycin.pl\/?page_id=206\",\"name\":\"Cancer Steam Cell (CSC) - Salinomycin\",\"isPartOf\":{\"@id\":\"https:\/\/salinomycin.pl\/#website\"},\"datePublished\":\"2021-09-13T08:35:56+00:00\",\"dateModified\":\"2023-08-02T12:32:41+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/salinomycin.pl\/?page_id=206#breadcrumb\"},\"inLanguage\":\"pl-PL\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/salinomycin.pl\/?page_id=206\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/salinomycin.pl\/?page_id=206#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Strona g\u0142\u00f3wna\",\"item\":\"https:\/\/salinomycin.pl\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cancer Steam Cell (CSC)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/salinomycin.pl\/#website\",\"url\":\"https:\/\/salinomycin.pl\/\",\"name\":\"Salinomycin\",\"description\":\"Strona informacyjna dotycz\u0105ca salinomycyny\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/salinomycin.pl\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"pl-PL\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Cancer Steam Cell (CSC) - Salinomycin","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/salinomycin.pl\/?page_id=206","og_locale":"pl_PL","og_type":"article","og_title":"Cancer Steam Cell (CSC) - Salinomycin","og_description":"Cancer Steam Cell (CSC) Wsp\u00f3\u0142czesna onkologia pomimo wielu lat do\u015bwiadcze\u0144 w walce z rakiem ma jeszcze wiele problem\u00f3w do rozwi\u0105zania. 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